D&S CLEANINGSan Francisco · Bay AreaHomes, apartments and biotech offices — residential and commercial.
South San Francisco keeps us busy on both sides of the business: family homes in Sunshine Gardens and Westborough, plus offices and labs near the biotech corridor that need after-hours commercial cleaning. Residential quotes come from the same instant calculator; office spaces get a custom commercial proposal.
Transparent pricing · Professional cleaners · No hidden surprises.

Residential Cleaning
Houses, condos and apartments cleaned by a professional, background-checked team.
Standard Cleaning
Routine upkeep for a home that is already in good shape — kitchens, baths, floors, dusting.
Deep Cleaning
Top-to-bottom detail with baseboards, buildup and hard-to-reach areas. Best for a first visit.
Recurring Cleaning
Weekly, every 2 weeks or every 4 weeks. Weekly visits save 10%, every 2 weeks saves 7%.
Move-In / Move-Out Cleaning
Deposit-ready detail including inside cabinets, oven and refrigerator.
Airbnb & Short-Term Rental Cleaning
Fast turnovers with fresh linens, restock checks and guest-ready presentation.
Office & Commercial Cleaning
Offices, studios and small commercial spaces — daytime or after hours, on your schedule.
Office managers near Oyster Point can request evening or weekend visits so cleaning never interrupts the workday.
ZIP codes served in South San Francisco: 94080, 94083
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Nearby areas we serve